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Visible Light‐Driven NADH Regeneration Sensitized by Proflavine for Biocatalysis
Author(s) -
Nam Dong Heon,
Park Chan Beum
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200115
Subject(s) - proflavine , biocatalysis , nad+ kinase , chemistry , photosynthesis , enzyme , biochemistry , catalysis , reaction mechanism , dna
Harvest time: Proflavine drives the reduction of NAD + in the presence of a Rh‐based electron mediator. Photoregenerated NADH was enzymatically active for oxidation by NADH‐dependent L ‐glutamate dehydrogenase for the synthesis of L ‐glutamate. This work suggests that proflavine has the potential to become an efficient light‐harvesting component in biocatalytic photosynthesis driven by solar energy.