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Engineered Unnatural Animals: Tools for Multicellular Biochemistry
Author(s) -
Mehl Ryan A.
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201100674
Subject(s) - multicellular organism , caenorhabditis elegans , toolbox , context (archaeology) , computational biology , computer science , biology , chemistry , biochemistry , programming language , cell , gene , paleontology
The tools at our disposal define the scientific problems we can solve. Few tools exist for studying and altering the components inside a living animal. The incorporation of unnatural amino acids site‐specifically into proteins in Caenorhabditis elegans greatly expands the toolbox currently available to biologists allowing for investigation of inter‐ and intracellular interactions in an organismal context.