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The Thorny Way to the Mechanism of Ribosomal Peptide‐Bond Formation
Author(s) -
Pech Markus,
Nierhaus Knud H.
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201100660
Subject(s) - peptide , ribosomal rna , peptide bond , chemistry , isotope , stereochemistry , mechanism (biology) , ribosome , biochemistry , philosophy , physics , rna , nuclear physics , epistemology , gene
Per aspera ad astra: Kinetic isotope effects have indicated a new and comprehensive picture of the central ribosomal enzymatic activity, peptide‐bond formation. To this end, isotopes were incorporated in the positions highlighted in red.