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Elaborate Nanoparticle‐Based Traps for Catching Cytosolic Players in the Act
Author(s) -
Delehanty James B.,
Medintz Igor L.
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201100589
Subject(s) - nanoclusters , ferritin , cytosol , nanoparticle , fluorescence , biophysics , intracellular , nanotechnology , molecule , chemistry , fluorescence microscope , materials science , biology , biochemistry , physics , organic chemistry , enzyme , quantum mechanics
Ferritin about: The Kim group has devised a nanoparticle‐based system for monitoring intracellular bimolecular interactions in real time. The system uses the rapid, innate self‐assembly of ferritin, expressing bait and prey molecules, into ordered nanoclusters whose morphology is tracked by using fluorescence microscopy.