Premium
Engineering Biofilms for Biocatalysis
Author(s) -
Tsoligkas Andreas N.,
Winn Michael,
Bowen James,
Overton Tim W.,
Simmons Mark J. H.,
Goss Rebecca J. M.
Publication year - 2011
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201100200
Subject(s) - biofilm , biocatalysis , biochemical engineering , synthetic biology , chemistry , computer science , computational biology , catalysis , biology , biochemistry , engineering , bacteria , reaction mechanism , genetics
Biofilm, friend not foe: Single species biofilms can be engineered to form robust biocatalysts with greater catalytic activity and significantly improved catalytic longevity than purified and immobilised enzymes. We report the engineering, structural analysis and biocatalytic capability of a biofilm that can mediate the conversion of serine and haloindoles to halotryptophans (see scheme).