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Six‐Colour HyBeacon Probes for Multiplex Genetic Analysis
Author(s) -
Richardson James A.,
Gerowska Marta,
Shelbourne Montserrat,
French David,
Brown Tom
Publication year - 2010
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201000623
Subject(s) - multiplex , multiplex polymerase chain reaction , computational biology , genetics , molecular diagnostics , gene , genetic analysis , biology , computer science , polymerase chain reaction
A combination of six HyBeacon probes has been used in multiplex genetic analysis to analyse mutations in the CFTR gene of PCR‐amplified human DNA. Multicolour HyBeacons of this type have great potential in human genetic screening and point‐of‐care diagnosis.