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Comparison of Staining Selectivity for Subcellular Structures by Carbazole‐Based Cyanine Probes in Nonlinear Optical Microscopy
Author(s) -
Zheng MeiLing,
Fujita Katsumasa,
Chen WeiQiang,
Smith Nicholas Isaac,
Duan XuanMing,
Kawata Satoshi
Publication year - 2011
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201000593
Subject(s) - cyanine , subcellular localization , carbazole , selectivity , staining , chemistry , microscopy , biophysics , fluorescence , nanotechnology , combinatorial chemistry , biochemistry , biology , materials science , photochemistry , cytoplasm , optics , physics , genetics , catalysis
Dyes for living cells: Carbazole‐based cyanine probes exhibit excellent properties such as subcellular staining selectivity, large two‐photon absorption cross sections, enhanced fluorescence when in their subcellular targets, and low toxicity. They provide a basis for nonlinear high‐resolution 3D imaging of subcellular structures, and may have future roles in drug delivery and investigating molecule transport within living cells.

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