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Extracellular Silica Nanocoat Confers Thermotolerance on Individual Cells: A Case Study of Material‐Based Functionalization of Living Cells
Author(s) -
Wang Guangchuan,
Wang Lijun,
Liu Peng,
Yan Yang,
Xu Xurong,
Tang Ruikang
Publication year - 2010
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201000494
Subject(s) - nanoshell , surface modification , extracellular , biocompatible material , layer (electronics) , biophysics , viability assay , chemistry , materials science , nanotechnology , microbiology and biotechnology , cell , chemical engineering , biochemistry , nanoparticle , biology , biomedical engineering , medicine , engineering
Cloaking device: Yeast cells were coated with a uniformly thin (about 100 nm) and continuous layer of biocompatible silica through a layer‐by‐layer chemical modification approach (see picture). Such a silica nanoshell forms an extracellular shield that endows these cells with enhanced defense against high temperature without significantly compromising cell viability.