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Targeted Gene Repair Facilitated by Peptide Nucleic Acids (PNA)
Author(s) -
Nielsen Peter E.
Publication year - 2010
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201000346
Subject(s) - nucleic acid , peptide nucleic acid , peptide , chemistry , biochemistry , computational biology , biology
Make or break: Recent developments in exploiting peptide nucleic acids (PNA) for specific target‐directed cellular and in vivo gene repair (see figure) are discussed in terms of possibilities and challenges.