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Peering into the Black Box of Fungal Polyketide Biosynthesis
Author(s) -
Weissman Kira J.
Publication year - 2010
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201000023
Subject(s) - polyketide , peering , biosynthesis , computational biology , biology , variety (cybernetics) , world wide web , genetics , computer science , gene , the internet , artificial intelligence
Fungi begin to reveal their secrets: Fungi elaborate a variety of polyketide secondary metabolites using three distinct biosynthetic machineries. Recent studies have started to reveal how these complicated multienzymes make specific biosynthetic “choices”.