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Cover Picture: Manipulation of Intracellular Auxin in a Single Cell by Light with Esterase‐Resistant Caged Auxins (ChemBioChem 13/2009)
Author(s) -
Kusaka Naoyuki,
Maisch Jan,
Nick Peter,
Hayashi Kenichiro,
Nozaki Hiroshi
Publication year - 2009
Publication title -
chembiochem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200990053
Subject(s) - auxin , intracellular , chemistry , microbiology and biotechnology , biochemistry , biophysics , biology , gene
The cover picture shows the concept of manipulating the intracellular auxin level by using light and photoliable caged auxin. Auxin is polar transported in plants so as to establish the auxin gradient required for normal plant growth. As the auxin gradient regulates many aspect of plant growth and development, the regulation of local auxin levels is very important. On p. 2195 ff, K. Hayashi et al. show how they designed and synthesized esterase‐resistant caged auxins to control the intracellular auxin level through photoirradiation. The esterase‐resistant caged auxin was stable within a plant cell and readily released auxin after photoirradiation. This caged‐auxin system enabled a spatial and temporal control of intracellular auxin levels. In fact, this system can manipulate the intracellular auxin level even in a single cell and modulate a cell's auxin response.