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Understanding and Exploiting Protein Prenyltransferases
Author(s) -
Nguyen Uyen T. T.,
Goody Roger S.,
Alexandrov Kirill
Publication year - 2010
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200900727
Subject(s) - prenylation , membrane protein , biochemistry , chemistry , computational biology , intracellular , transport protein , biology , membrane , enzyme
Lipidating proteins: Protein prenylation is catalyzed by protein prenyltransferases, and enables proteins to reversibly associate with intracellular membranes. The mechanisms of protein prenylation and the recent developments in analysis and biotechnological exploitation of these modifications are reviewed.