Premium
Protein Conjugates of SH3‐Domain Ligands and ATP‐Competitive Inhibitors as Bivalent Inhibitors of Protein Kinases
Author(s) -
Tiwari Rakesh,
Parang Keykavous
Publication year - 2009
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200900462
Subject(s) - bivalent (engine) , kinase , chemistry , conjugate , sh3 domain , biochemistry , proto oncogene tyrosine protein kinase src , mathematical analysis , mathematics , organic chemistry , metal
Double trouble : Designing bivalent inhibitors of protein kinases by using a protein (hAGT) as a spacer between SH3‐domain‐binding ligands and an ATP‐binding‐site inhibitors is described.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom