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DNA Monofunctionalization of Quantum Dots
Author(s) -
Carstairs Helen M. J.,
Lymperopoulos Kostas,
Kapanidis Achillefs N.,
Bath Jonathan,
Turberfield Andrew J.
Publication year - 2009
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200900300
Subject(s) - quantum dot , dna , streptavidin , nanotechnology , computational biology , chemistry , physics , computer science , microbiology and biotechnology , biology , genetics , materials science , biotin
Dots as pure as the driven snow : A method to purify streptavidin‐coated quantum dots functionalized with a single short DNA duplex from an inhomogeneous population is presented. A high percentage (∼86 %) of the monofunctionalized quantum dots present in the original sample are recovered. Hybridization of the attached DNA after purification is demonstrated.