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Development of a Fluorescent Peptide for the Detection of Vascular Endothelial Growth Factor (VEGF)
Author(s) -
Suzuki Yoshio,
Yokoyama Kenji
Publication year - 2009
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200900190
Subject(s) - reagent , fluorescence , vegf receptors , vascular endothelial growth factor , chemistry , peptide , chromatography , biochemistry , biology , cancer research , organic chemistry , physics , quantum mechanics
Held down and lit up : We report a new fluorescence‐based reagent for the detection and quantification of VEGF. The fluorescence intensity of the reagent increased upon binding to VEGF, as illustrated here. Immobilization of the reagent onto a plate facilitated the successful detection of VEGF in serum by using fluorescence spectrometry. This reagent is a good VEGF indicator and could find wide applications for the convenient detection of VEGF.