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A Mechanism for Stochastic Decision Making by Bacteria
Author(s) -
Hensel Zach,
Xiao Jie
Publication year - 2009
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200800824
Subject(s) - mechanism (biology) , bacteria , biochemical engineering , computational biology , computer science , chemistry , biology , engineering , genetics , epistemology , philosophy
What mechanism underlies the induction of the lac operon? Expression from the lac operon is an all‐or‐none phenomenon. Recent work by Choi et al. combines single‐molecule imaging of gene expression with single‐cell induction measurements to develop a stochastic model describing the critical role of single lac ‐repressor molecules in induction.