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Identification of a Toxic Peptide through Bidirectional Expression of Small RNAs
Author(s) -
Mok Wendy W. K.,
Navani Naveen K.,
Barker Courtney,
Sawchyn Bobbijo L.,
Gu Jimmy,
Pathania Ranjana,
Zhu Rebecca D.,
Brown Eric D.,
Li Yingfu
Publication year - 2009
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200800591
Subject(s) - rna , identification (biology) , computational biology , biology , small rna , gene , phenotype , small nucleolar rna , gene expression , transfer rna , microrna , long non coding rna , genetics , microbiology and biotechnology , botany
Identifying lethal sRNA genes : We established a novel screening strategy that integrates the use of an RNA expression system to search uncharacterized small RNAs and their antisense counterparts for lethal phenotype.