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Oligosaccharide‐Mediated Nuclear Transport of Nanoparticles
Author(s) -
Niikura Kenichi,
Sekiguchi Shota,
Nishio Takashi,
Masuda Tomoya,
Akita Hidetaka,
Matsuo Yasutaka,
Kogure Kentaro,
Harashima Hideyoshi,
Ijiro Kuniharu
Publication year - 2008
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200800464
Subject(s) - maltotriose , digitonin , monosaccharide , nanoparticle , hela , chemistry , biophysics , oligosaccharide , quantum dot , nuclear transport , nucleus , biochemistry , nanotechnology , cell nucleus , microbiology and biotechnology , cell , membrane , materials science , biology , maltose , enzyme , gene
Door openers . We investigated the efficiency of oligo‐α‐glucopyranosides to mediate the nuclear import of nanoparticles into digitonin‐permeabilized HeLa cells. It was found that maltotriose‐displaying quantum dots (QDs) were specifically transported into the nucleus, whereas monosaccharide‐displaying QDs did not.