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Design of Lectin Mimetics
Author(s) -
Mazik Monika
Publication year - 2008
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200800038
Subject(s) - lectin , disaccharide , chemistry , carbohydrate , receptor , biochemistry , computational biology , stereochemistry , biology
A powerful carbohydrate receptor , which can be seen as a “synthetic lectin”, has recently been developed by Davis et al. The meta ‐terphenyl‐based tetracyclic receptor was inspired by carbohydrate‐binding proteins, and was designed to provide both polar and apolar contacts to a disaccharide molecule. Image taken from ref. 9 with permission. Copyright 2007, American Association for the Advancement of Science.