Premium
A Versatile Gold Surface Approach for Fabrication and Interrogation of Glycoarrays
Author(s) -
Zhi ZhengLiang,
Laurent Nicolas,
Powell Andrew K.,
Karamanska Rositsa,
Fais Margherita,
Voglmeir Josef,
Wright Adam,
Blackburn Jonathan M.,
Crocker Paul R.,
Russell David A.,
Flitsch Sabine,
Field Rob A.,
Turnbull Jeremy E.
Publication year - 2008
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200700788
Subject(s) - interrogation , nanotechnology , glycomics , monolayer , glycan , fluorescence , fabrication , chemistry , computer science , combinatorial chemistry , materials science , physics , optics , biochemistry , medicine , alternative medicine , archaeology , pathology , glycoprotein , history
Glycoarrays on gold : A designer gold surface incorporating a self‐assembled monolayer with weak protein absorption properties has been optimised for rapid display and interrogation of both native and derivatised glycans in array formats. This rapid, facile approach has diverse applications in glycomics, through exploitation of fluorescence, SPR and MALDI‐ToF MS detection methods.