Synthesis of a Stimulus‐Responsive Processing Device and Its Application to a Nucleocytoplasmic Shuttle Peptide | Zendy

Shigenaga Akira | Zendy; Tsuji Daisuke | Zendy; Nishioka Naomi | Zendy; Tsuda Shugo | Zendy; Itoh Kohji | Zendy; Otaka Akira | Zendy

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Synthesis of a Stimulus‐Responsive Processing Device and Its Application to a Nucleocytoplasmic Shuttle Peptide

Author(s) -

Shigenaga Akira,

Tsuji Daisuke,

Nishioka Naomi,

Tsuda Shugo,

Itoh Kohji,

Otaka Akira

Publication year - 2007

Publication title -

chembiochem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.200700442

Subject(s) - stimulus (psychology) , nuclear localization sequence , peptide , chemistry , information processing , fluorophore , biophysics , computer science , microbiology and biotechnology , neuroscience , biochemistry , biology , psychology , physics , fluorescence , quantum mechanics , cytoplasm , psychotherapist

Stimulus and response . Stimulus‐responsive processing (peptide bond cleavage) devices were developed. The processing reaction was triggered by stimulus‐induced removal of a PG, and the processing products were obtained in good purity. A photo‐responsive processing device was successfully applied to develop a nucleocytoplasmic shuttle peptide. (F: fluorophore, NES: nuclear export signal. NLS: nuclear localization signal. PG: stimulus‐responsive protective group)

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