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Biosynthesis of Nitro Compounds
Author(s) -
Winkler Robert,
Hertweck Christian
Publication year - 2007
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200700042
Subject(s) - nitration , nitro , chemistry , natural product , enzyme , biosynthesis , nitro compound , aryl , combinatorial chemistry , biochemistry , organic chemistry , alkyl
Green nitro . While many nitrated natural products from a variety of sources have been isolated, their biosynthetic origin is less well understood. Two routes can lead to these highly energetic natural products: biological aryl nitration and highly selective enzymatic N‐oxidation. Despite the numerous nitrated natural products, only a few of the enzymes involved in nitro group formation have been identified, and only recently have mechanistic studies provided insight into these reactions.