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Cascade Signal Amplification for DNA Detection
Author(s) -
Tian Ye,
He Yu,
Mao Chengde
Publication year - 2006
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200600336
Subject(s) - dna , detection limit , loop mediated isothermal amplification , cascade , limit (mathematics) , signal (programming language) , protein detection , enzyme , computational biology , microbiology and biotechnology , multiple displacement amplification , chemistry , biological system , biology , biophysics , nanotechnology , computer science , polymerase chain reaction , dna extraction , biochemistry , chromatography , materials science , gene , mathematics , mathematical analysis , programming language
Bigger and bigger . A novel, isothermal DNA detection method has been developed that contains two successive amplifications and integrates both a protein enzyme and a DNA enzyme. The current detection limit is 1 p M .