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Artificial Metalloenzymes for Enantioselective Catalysis: Recent Advances
Author(s) -
Letondor Christophe,
Ward Thomas R.
Publication year - 2006
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200600264
Subject(s) - enantioselective synthesis , catalysis , chemistry , combinatorial chemistry , nanotechnology , organic chemistry , materials science
Creating new catalytic function in proteins . Anchoring an organometallic moiety within a protein affords artificial metalloenzymes for enantioselective catalysis. Both chemical and genetic tools can be applied in the optimization of such systems, which lie at the interface between homogeneous and enzymatic catalysis. This minireview presents the latest developments in the field of artificial metalloenzymes.