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Chemical Microarrays to Identify Ligands that Bind Pathogenic Cells
Author(s) -
Barrett Olivia J.,
Childs Jessica L.,
Disney Matthew D.
Publication year - 2006
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200600260
Subject(s) - tryptamine , dna microarray , microarray , ligand (biochemistry) , computational biology , chemistry , microarray analysis techniques , tissue microarray , biochemistry , biology , gene , gene expression , genetics , receptor , cancer
Tryptamine trial . Chemical microarrays have been used to identify ligands that recognize the surface of a variety of pathogenic organisms. In each case, the highest affinity ligand is tryptamine, which is shown to recognize cell surfaces when multivalently displayed on a microarray surface or on a water‐soluble polymer.
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