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Bioassay Labels Based on Apoferritin Nanovehicles
Author(s) -
Liu Guodong,
Wang Jun,
Lea Scott A,
Lin Yuehe
Publication year - 2006
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200600225
Subject(s) - bioassay , nanoparticle , nanotechnology , chemistry , combinatorial chemistry , materials science , biology , genetics
A simpler label . Various redox and optical markers have been easily loaded in the cavity of apoferritin to develop novel and versatile nanoparticle labels for optical and electrochemical bioassays. Such use of apoferritin nanovehicles offers convenient loading and releasing of the markers of interest by pH control instead of harsher conditions and avoids complicated nanoparticle syntheses. The new nanoparticle labels could be applicable to other biological assays, particularly immunoassays.