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Artificial Metalloproteins with a Ruthenium Tris(bipyridyl) Complex as the Core
Author(s) -
Ishida Hitoshi,
Maruyama Yuji,
Kyakuno Masato,
Kodera Yoshio,
Maeda Tadakazu,
Oishi Shigero
Publication year - 2006
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200600162
Subject(s) - ruthenium , metalloprotein , chemistry , peptide , tris , amino acid , combinatorial chemistry , amino acid residue , stereochemistry , peptide sequence , organic chemistry , biochemistry , catalysis , enzyme , gene
Peptide origami . A peptide containing three residues of 5′‐amino‐2,2′‐bipyridine‐5‐carboxylic acid (5 Bpy) as an unnatural amino acid has been folded by coordination with a ruthenium(II) ion to generate an artificial metalloprotein. Four isomers were separated by HPLC and identified by MALDI‐TOF‐MS. Each isomer was further characterized by absorption, emission, and CD spectra.