Recognition on the Nanoscale of a DNA Sequence by an Inorganic Crystal Surface | Zendy

Scipioni Anita | Zendy; Pisano Sabrina | Zendy; Bergia Anna | Zendy; Savino Maria | Zendy; Samorì Bruno | Zendy; De Santis Pasquale | Zendy

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Recognition on the Nanoscale of a DNA Sequence by an Inorganic Crystal Surface

Author(s) -

Scipioni Anita,

Pisano Sabrina,

Bergia Anna,

Savino Maria,

Samorì Bruno,

De Santis Pasquale

Publication year - 2006

Publication title -

chembiochem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.200600079

Subject(s) - mica , nanoscopic scale , sequence (biology) , dna , field (mathematics) , surface (topology) , nanotechnology , dna sequencing , palindrome , palindromic sequence , atomic force microscopy , crystal (programming language) , computational biology , crystallography , chemistry , computer science , biology , materials science , gene , biochemistry , mathematics , paleontology , genome , geometry , pure mathematics , programming language

Statistical analysis of the profiles of palindromic DNA molecules imaged by atomic force microscopy provided evidence of the capability of a mica surface of recognizing DNA sequences. The differential free energy involved in this collective recognition process was estimated. A tentative model based on sequence‐dependent imbalances of the electrostatic field normal to the surface ( E ) along the chain is proposed.

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