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Monitoring Chemical Reactions by Using Ion‐Channel‐Forming Peptides
Author(s) -
Blake Steven,
Mayer Thomas,
Mayer Michael,
Yang Jerry
Publication year - 2006
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200500532
Subject(s) - ion channel , chemistry , channel (broadcasting) , reagent , molecule , chemical modification , combinatorial chemistry , nanotechnology , computer science , biochemistry , materials science , telecommunications , organic chemistry , receptor
Current affairs . We demonstrate that it is possible to detect the conversion of reactive chemical groups on molecules attached to gramicidin A in the presence of external chemical reagents, such as KNO 2 , by monitoring the change in single‐channel conductances across planar lipid bilayers.