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Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns
Author(s) -
Pilobello Kanoelani T.,
Krishnamoorthy Lakshmipriya,
Slawek Deepika,
Mahal Lara K.
Publication year - 2005
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200400403
Subject(s) - glycosylation , lectin , computational biology , microarray analysis techniques , glycoprotein , computer science , biology , bioinformatics , biochemistry , gene , gene expression
Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin microarray for the rapid analysis of protein glycopatterns (see scheme).