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The Chemistry and Biology of Nitroxyl (HNO): A Chemically Unique Species with Novel and Important Biological Activity
Author(s) -
Fukuto Jon M.,
Dutton Andrew S.,
Houk Kendall N.
Publication year - 2005
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200400271
Subject(s) - nitroxyl , chemistry , nanotechnology , combinatorial chemistry , organic chemistry , materials science
Small species, big impact . Nitroxyl (HNO) is chemically unique and biologically important. In the past few years, major discoveries of its novel biological actions have been made as well as revelations regarding its fundamental chemistry. These new findings, for example those relating to the relative energies of the various nitroxyl species (see figure) are presented and discussed.