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A Spectrum of Models of Signaling Pathways
Author(s) -
Vayttaden Sharat J.,
Ajay Sriram M.,
Bhalla Upinder S.
Publication year - 2004
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200400127
Subject(s) - computational biology , signal transduction , chemistry , biology , microbiology and biotechnology
How ready is biology for systems biology? This review surveys some 250 models and supporting experiments to assess how well major signaling pathways have been quantified. The review traces the family tree of MAPK models to show how modeling can evolve and has influenced the field.