Premium
The Molecular Arrangement of Membrane‐Bound Annexin A2‐S100A10 Tetramer as Revealed by Scanning Force Microscopy
Author(s) -
Menke Manuela,
Ross Michaela,
Gerke Volker,
Steinem Claudia
Publication year - 2004
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200400004
Subject(s) - tetramer , annexin , annexin a2 , membrane , chemistry , biophysics , microscopy , annexin a1 , biochemistry , biology , cell , physics , optics , enzyme
The first step in membrane aggregation mediated by the annexin A2‐S100A10 heterotetrameric complex (annexin A2t) has been unraveled by in situ scanning force microscopy. It has been shown unambiguously that annexin A2t binds to solid‐supported lipid bilayers simultaneously with both annexin A2 subunits.