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A Fusion of Disciplines: Chemical Approaches to Exploit Fusion Proteins for Functional Genomics
Author(s) -
Johnsson Nils,
Johnsson Kai
Publication year - 2003
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.200200603
Subject(s) - computational biology , functional genomics , proteomics , fusion protein , genomics , fusion , biology , chemistry , genome , genetics , gene , recombinant dna , linguistics , philosophy
Playing tag : The specific labeling of fusion proteins with small molecules in vivo (see figure, X represents the small molecule) offers the possibility of providing proteins with functions that can not be genetically encoded and may allow the use of a single fusion protein for a variety of different applications. In this Minireview, different approaches for achieving such in vivo labeling and their importance for functional genomics and proteomics are discussed.