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Glutathione reductase (EC 1.6.4.2.) in experimental trypanosomiasis
Author(s) -
Nok Andrew J.,
Onyenekwe Paul C.,
Ibrahim Sani,
Bature Asabe,
Ogbadoyi Emmanuel
Publication year - 1995
Publication title -
cell biochemistry and function
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.933
H-Index - 61
eISSN - 1099-0844
pISSN - 0263-6484
DOI - 10.1002/cbf.290130212
Subject(s) - glutathione reductase , glutathione , oxidative stress , parasitemia , trypanosoma , gpx4 , reductase , trypanosomiasis , kidney , biology , biochemistry , chemistry , glutathione peroxidase , enzyme , virology , immunology , endocrinology , malaria , plasmodium falciparum
The activity of glutathione reductase (GHSR) in extracts of kidney, liver and testis of rats infected with Trypanosoma congolense decreased with every wave of parasitemia. The implications of these observations as they relate to the risk of oxidative stress are discussed.