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Brain Na + K + ATPase and cholesterol in acute experimental trypanosomiasis
Author(s) -
Nok Andrew J.,
Esievo K. A. N.,
Ukoha A. I.,
Ikediobi C. O.,
Ibrahim S.,
Martins O.,
Tekdek B.,
Omage J.
Publication year - 1992
Publication title -
cell biochemistry and function
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.933
H-Index - 61
eISSN - 1099-0844
pISSN - 0263-6484
DOI - 10.1002/cbf.290100404
Subject(s) - cholesterol , trypanosomiasis , radiochemistry , physics , chemistry , virology , biochemistry , biology
Brain Na + K + ATPase activity has been found to decrease in experimental trypanosomiasis in rats infected with Trypanosoma congolense . Some physical features that affect membrane fluidity were also observed to be altered. The levels of cholesterol in the brain and free fatty acids in the serum were found to increase in the infected animals. These findings might be relevant to the development of brain lesions.