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Antiproliferative effects of some N ‐benzylideneanilines
Author(s) -
Özkay Yusuf,
İncesu Zerrin,
Işıkdağ İlhan,
Yeşilkaya Mehmet
Publication year - 2008
Publication title -
cell biochemistry and function
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.933
H-Index - 61
eISSN - 1099-0844
pISSN - 0263-6484
DOI - 10.1002/cbf.1406
Subject(s) - hela , cytotoxic t cell , chemistry , stereochemistry , cell culture , mass spectrometry , cell , microbiology and biotechnology , biochemistry , cancer research , in vitro , biology , chromatography , genetics
A series of Schiff bases including N ‐benzylideneaniline (NBA) nuclei were prepared. The chemical products obtained were characterized by mass spectometry (APCI), 1 H NMR, and IR spectroscopy in order to seek their cytotoxic and proliferation effects on human small lung (A549) and cervical (HeLa) cancer cell lines with biochemical assays. All of the synthesized compounds showed antiproliferative effects to different extents. Copyright © 2007 John Wiley & Sons, Ltd.