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Chiral Metal Carbene Modified [2.2]Metacyclophanes: Synthesis, Structure, and Chiroptic Properties
Author(s) -
Lougen Andrea,
Vögtle Fritz,
Dötz Karl Heinz,
Nieger Martin
Publication year - 1997
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19971300812
Subject(s) - carbene , chemistry , aminolysis , chromium , metal , stereochemistry , cyclophane , medicinal chemistry , polymer chemistry , molecule , organic chemistry , catalysis
Pentacarbonyl( 4 ‐[2.2]metacyclophanyl(methoxy)carbene)‐chromium(0) ( 6 ) was prepared according to the Fischer route from 4‐bromo[2.2]metacyclophane. Aminolysis with non‐chiral and chiral amines affords aminocarbene complexes 7 ‐12 . X‐Ray structure analyses for 6 and its aminocarbene analogs 7 and 8 indicate that the incorporation of the chromium‐carbene fragment has no significant influence on the deformation of the [2.2]metacyclophane skeleton.