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Metallkomplexe mit biologisch wichtigen Lisganden, LXXX . (η 3 :η 3 ‐C 10 H 16 )Ru(IV)‐Komplexe mit α‐Aminocarboxylaten, α‐Aminosäureestern und Peptidestern als Liganden
Author(s) -
Severin Kay,
Mihan Shahram,
Beck Wolfgang
Publication year - 1995
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19951281110
Subject(s) - chemistry , ligand (biochemistry) , stereochemistry , chelation , chloride , medicinal chemistry , metal , histidine , amino acid , organic chemistry , biochemistry , receptor
Metal Complexes Containing Biologically Important Ligands, LXXX LXXIX. Mitteilung: Lit. . — (η 3 :η 3 ‐C 10 H 16 )Ru(IV) Complexes with α‐Amino Carboxylates, α‐Amino Acid Esters, and Peptide Esters as Ligands Reactions of the chloro‐bridged bis(allyl) complex [(η 3 :η 3 ‐C 10 H 16 )Ru(Cl)(μ‐Cl)] 2 with α‐amino carboxylates and α‐amino acid esters afford the complexes (η 3 :η 3 ‐C 10 H 16 )(Cl)RuNH 2 CHRCO 2 ( 2 ) and (η 3 :η 3 ‐C 10 H 16 )(Cl) 2 ‐RuNH 2 CHRCO 2 R′ ( 3 ). Abstraction of chloride from 3 by Ag + gives the N,O ‐chelates [(η 3 :η 3 ‐C 10 H 16 )(Cl)RuNH 2 CHRCO 2 R′] + BF4 ( 4 ). Cysteine methyl ester forms the N,S ‐chelate complex (η 3 :η 3 ‐C 10 H 16 )(Cl)RuNH 2 CH(CO 2 CH 3 )CH 2 S ( 5 ), and with histidine methyl ester a dinuclear complex 6 with N,N ‐histidine bridge is obtained. Compound 3d with L‐PheOEt as ligand was characterized by X‐ray diffraction.