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Molekulare Pinzetten aus Cyclophan‐Bausteinen
Author(s) -
Güther Ralf,
Nieger Martin,
Rissanen Kari,
Vögtle Fritz
Publication year - 1994
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19941270426
Subject(s) - cyclophane , chemistry , molecular tweezers , stereochemistry , molecule , tweezers , crystallography , supramolecular chemistry , organic chemistry
Molecular Tweezers from Cyclophane Building Blocks Molecular tweezer compounds 1 – 6 with convergent carboxyl groups are prepared from suitable functionalized [2.2]‐and dithia[3.3]metacyclophane building blocks by using several multistep strategies. The CC coupling of two cyclophanes according to the Hagihara method leads to alkynespacered double cyclophanes. These new preorganized, acyclic host compounds of the cyclophane‐type react as molecular tweezers and can selectively “grasp” guest molecules and bind them strongly. X‐ray analyses underline the syn conformations of the dithia[3.3]‐ and the anti conformation of the [2.2]metacyclophanes.