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Metallkomplexe mit biologisch wichtigen Liganden, LXX. Synthese, Stereochemie und Reaktionen von Ruthenium(II) und Osmium(II)‐Komplexen mit α‐Aminocarboxylat‐Liganden
Author(s) -
Severin Kay,
Sünkel Karlheinz,
Beck Wolfgang
Publication year - 1994
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19941270406
Subject(s) - chemistry , osmium , ruthenium , formic acid , crystal structure , medicinal chemistry , stereochemistry , oxidative addition , chelation , metal , ligand (biochemistry) , catalysis , organic chemistry , biochemistry , receptor
Metal Complexes of Biologically Important Ligands, LXX [1] .‐ Synthesis, Stereochemistry and Reactions of Ruthenium(II) and Osmium(II) Complexes with α‐Amino Carboxylates Herrn Professor Helmut Werner zum 60. Geburtstag gewidmet. The reactions of MHCl(CO)(PPh 3 ) 3 with salts of α‐amino acids give the hydrido‐N,O‐chelate complexes MH(CO)(NH 2 CHR‐COO)(PPh 3 ) 2 ( 1a – g ;) M = Ru, Os). Complexes 1a – c can alternatively be prepared by oxidative addition of the appropriate α‐amino acid to Ru(CO) 3 (PPh 3 ) 2 . The crystal structure of 1b has been determined by an X‐ray structural analysis. The leucinato compound 1c is an effective catalyst for the decomposition of formic acid. In contrast, reactions of RuHCl‐(CO)(PPh 3 ) 3 with α‐amino acids afford the chloro‐N,O‐che‐late complexes RuCl(CO)(NH 2 CHRCOO)(PPh 3 ) 2 2a – h . The decomposition reactions of 2c, 2g and 2h have been investigated.