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Reaktive 3,4‐disubstituierte Derivate des 1,6‐Methano[10]annulens und ihr Synthesepotential
Author(s) -
Neidlein Richard,
Schröder Günter
Publication year - 1992
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19921251009
Subject(s) - chemistry , annulene , cycloheptatriene , medicinal chemistry , stereochemistry
Reactive 3,4‐Disubstituted Derivatives of 1,6‐Methano[10]annulene and their Synthetic Possibilities Ethyl 4‐bromo‐1,6‐methano[10]annulene‐3‐carboxylate ( 4 ) is synthesized in three steps from cycloheptatriene‐1,6‐dicarbaldehyde 1 . The key step of this conversion is a highly selective monoolefination of 1 . The synthetic possibilities of 4 are discussed.
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