Premium
Triazolines, XXXI [1] Reaction of 5‐Amino‐4,5‐dihydro‐4‐methylene‐1 H ‐1,2,3‐triazoles with Substituted Thiazolium‐4‐olates
Author(s) -
Cavalleri Paolo,
Clerici Francesca,
Erba Emanuela,
Trimarco Pasqualina
Publication year - 1992
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19921250419
Subject(s) - chemistry , methylene , cycloaddition , octane , raney nickel , medicinal chemistry , organic chemistry , catalysis
The cycloaddition reaction of 5‐amino‐ v ‐triazolines 2 with thiazolium‐4‐olates 1 affords two isomeric cycloadducts 3 and 4 . A synthetic utilization has been achieved by their desulfuration: The cycloadducts 3 and 4 are catalytically transformed with Raney nickel to pyridinones 5 . The acid‐catalized rearrangement of 3 and 4 affords the 8‐thia‐6‐azabicyclo[3.2.1]‐octane derivatives 6 .