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2‐Chloro‐4,5‐dihydroimidazole, VI. Annulation by Means of 4‐(Dimethylamino)pyridine in the Presence of C — H Acids
Author(s) -
Sączewski Franciszek
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911240942
Subject(s) - chemistry , pyridinium , pyridine , annulation , yield (engineering) , salt (chemistry) , medicinal chemistry , stereochemistry , organic chemistry , catalysis , materials science , metallurgy
2‐Chloro‐4,5‐dihydroimidazole ( 1 ) reacts with 4‐(dimethylamino)pyridine to yield the stable pyridinium salt 2 , which on treatment with some C — H acids produces 1,2,3,5‐tetrahydroimidazo[1,2‐α]pyrimidines 6 .