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Improved Synthesis of Fluoromethanesulfonyl Chloride
Author(s) -
Lange Ulla,
Senning Alexander
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911240829
Subject(s) - chemistry , nucleophilic substitution , chloride , sulfide , ether , fluorine , nucleophile , organic chemistry , medicinal chemistry , crown ether , ion , catalysis
Abstract Introduction of fluorine into 4‐chlorobenzyl chloromethyl sulfide ( 7 ) by crown‐ether‐assisted nucleophilic substitution furnishes 4‐chlorobenzyl fluoromethyl sulfide ( 5 ), a key intermediate for the preparation of fluoromethanesulfonyl chloride ( 1 ).