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Geminal‐Dialkyl‐Effect‐Controlled Site Selectivity of Fe(I)‐Mediated C H/C C Bond Activation of Aliphatic Ketones
Author(s) -
Schröder Detlef,
Bowie John H.,
Stringer M. B.,
Schwarz Helmut
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911240733
Subject(s) - geminal , chemistry , dehydrogenation , selectivity , alkyl , medicinal chemistry , ketone , stereochemistry , organic chemistry , catalysis
Depending on the internal energy content, due to the operation of a geminal dialkyl effect, the Fe + ‐mediated dehydrogenation of α,α‐dimethyl‐substituted ketones preferably involves the more substituted alkyl chain.