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Reaktionen von Komplexliganden, XLIII. Optisch aktive Aminocarben‐Komplexe: Reagentien für die regiospezifische und diastereoselektive Synthese von γ‐Lactamen
Author(s) -
Dötz Karl Heinz,
Weber Rita
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911240726
Subject(s) - chemistry , aminolysis , optically active , reagent , carbene , stereochemistry , medicinal chemistry , organic chemistry , catalysis
Reactions of Complex Ligands, XLIII. ‐ Optically Active Aminocarbene Complexes: Reagents for the Regiospecific and Diastereoselective Synthesis of γ‐Lactams Optically active pentacarbonyl[amino(aryl)carbene] complexes 2 ‐ 5 of chromium have been obtained by aminolysis of methoxycarbene complexes 1 with L‐amino acid esters. The alanyl and phenylalanyl compounds 2, 3 react with 1‐octyne regiospecifically and moderately diastereoselectively to give the pyrrolinones 6 , 7 .