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Medizinisch interessante Metallchelate, III. 99m Tc‐Komplexe mit vierzähnigen Dibrenzkatechin‐Liganden
Author(s) -
Ekkehardt Hahn F.,
Rupprecht Stefan
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911240311
Subject(s) - chemistry , amine gas treating , ligand (biochemistry) , medicinal chemistry , metal , chelation , stereochemistry , inorganic chemistry , organic chemistry , biochemistry , receptor
Metal Chelates of Medical Interest, III. – 99m Tc Complexes with Tetradentate Dicatechol Ligands The dicatechol ligand bis[3‐(2,3‐dihydroxyphenoxy)propyl]‐amine hydrochloride, DIPACE ( 6 ), reduces the 99m [TcO 4 ] − ion to lower valent 99m Tc and subsequently forms a complex with the reduced 99m Tc. The structure of benzylbis[3‐(2,2‐dimethyl‐1,3‐benzodioxol‐4‐yloxy)propyl]amine ( 4 ) is determined by X‐ray crystallography.