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Concave Reagents, 7 1) Concave Benzoic Acids
Author(s) -
Lüning Ulrich,
Wangnick Carsten,
Peters Karl,
Schnering Hans Georg Von
Publication year - 1991
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19911240225
Subject(s) - chemistry , reagent , benzoic acid , titration , halogenation , terphenyl , stereochemistry , organic chemistry , medicinal chemistry
Based on m ‐terphenyl units, concave benzoic acids 11a and 12a were prepared via the 2,6‐diarylbenzoic acid 7a . Bromination of 7a with NBS gave 9 , and cyclization of 9 with dithiols 10 led to the bimacrocyclic concave acids 11a and 12a . Their relative acidities were determined by photometric titrations in ethanol, and the three‐dimensional structure of 11a was determined by X‐ray analysis.