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1,4‐Dioxino[2,3‐ b ]pyridine und 1,4‐Oxathiino[2,3‐ b ]pyridine
Author(s) -
Neunhoeffer Hans,
Sponheimer Otto
Publication year - 1990
Publication title -
chemische berichte
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 0009-2940
DOI - 10.1002/cber.19901231230
Subject(s) - chemistry , pyridine , sodium hydride , medicinal chemistry , hydride , stereochemistry , organic chemistry , hydrogen
1,4‐Dioxino[2,3‐ b ]pyridines and 1,4‐Oxathiino[2,3‐ b ]pyridines 1,4‐Dioxino[2,3‐ b ]pyridine and 1,4‐Oxathiino[2,3‐ b ]pyridine Reaction of 3‐hydroxy‐2‐pyridones 1 or 3‐hydroxy‐2‐pyridinthiones 2 with sodium hydride and 1,2‐dibromoethane in hexamethylphosphorous triamide gives 1,4‐dioxino[2,3‐ b ]pyridines 3 and 1,4‐oxathiino[2,3‐ b ]pyridines 5 which can be hydrogenated to amino‐1,4‐dioxino[2,3‐ b ]pyridines 7 .
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